P-37  BLOCKAGE OF ABCC1/MPR1 EXPRESSION ENHANCED CHEMOTHERAPEUTIC EFFICACY VIA THE MANUPULATION OF NRF2 IN HUMAN ETOPOSIDE-RESISTANT ORAL CANCER CELLS

Huang-Hui Chen, Yen-Ting Cheng, Wen-Yang Lai, Jang-Yang Chang, Ching-Chuan Kuo

National Institute of Cancer Research, National Health Research Institutes, Taiwan

P-38  Kiss-1 suppresses MMP-9 expression by activating with p38 MAP kinase in human stomach cancer

Kyung Hee Lee¹, Eun Young Choi², Min Kyoung Kim², Byung Ik Jang³, Tae Nyeun Kim³, Sang Woon Kim⁴, Sun Kyo Song⁴, Jae-Ryong Kim⁵

¹Department of Oncology, Korea, ²Department of Hematology-Oncology, ³Gastroenterology, ⁴Surgery, ⁵Biochemistry and Molecular Biology

P-39  A QUANTITATIVE ANALYSIS OF CpG METHYLATION OF THE TRANSCRIPTION FACTOR 4 GENE IN GASTRIC CARCINOMA USING PYROSEQUENCING

Dong Yi Kim¹, Chan Yong Park¹, Chang Hyun Kim¹, Jae Kyoon Joo¹, Ho Gun Kim¹, Seong Yeob Ryu¹, Young Kyu Park¹, O Jung¹, Jae Hyuk Lee², Mi Ran Jung¹

¹Surgery, Chonnam National University Medical School, Korea, ²Department of Pathology, Chonnam National University Hospital

P-40  Modulation of Intestinal Epithelial Cell-Derived Cytokine Secretion via Mistletoe Lectin

Suyun Lyu¹, Wonbong Park², Chang-Eui Hong¹, Sun-Myung Yun¹, Min-Joo Kim¹, Myung-Chan Cho¹, Ho-Am Jang¹, Seong-Taek Jee¹

¹Department of Herbal Medicinal Pharmacology, Daegu Haany University, Korea, ²Department of Chemistry, Seoul Women' University

P-41  ENHANCEMENT OF PROTOPORPHYRIN IX ACCUMULATION BY ALGINATE-INCORPORATED AND FOLIC ACID-CONJUGATED CHITOSAN NANO-PARTICLES FOR COLORECTAL CANCER PHOTODYNAMIC DETECTION

Shu-Jyuan Yang, Kun-Che Tsai, Feng-Huei Lin, Ming-Jium Shieh

Institute of Biomedical Engineering, National Taiwan University, Taiwan

P-42  DETECTION OF EGFR GENE MUTATION AND GENE AMPLIFICATION IN COLORECTAL CANCER

Shanna Chen, Shan-Na Chen, Li-Hui Chow, Tsang-Wu Liu

Division of Cancer Research, National Health Research Institutes, Taiwan

P-43  A comparative study of protein expressions in primary colorectal cancer and synchronous hepatic metastases: The significance of MMP-1 expression

Young Wan Kim^1,2, Youg Taek Ko¹, Nam Kyu Kim¹, Chung Hyun Cheol³, Byung Soh Min¹, Kang Young Lee¹, Hoguen Kim⁴

¹Surgery, Yonsei University, Korea, ²Department of Surgery, Yonsei University College of Medicine, Korea, ³Department of Medicine, Yonsei University College of Medicine, Korea, ⁴Department of Pathology, Yonsei University College of Medicine, Korea

P-44  Cell Death of Colorectal Cancer Stem-Like Cell Was Induced by Photodynamic Therapy with Protoporphyrin IX

Ming-Feng Wei¹, Shiang-You Han¹, Shu-Jyuan Yang¹, Feng-Huei Lin¹, Shih-Chieh Hung², Ming-Jium Shieh¹

¹Institute of Biomedical Engineering, National Taiwan University, Taiwan, ²Institute of Clinical Medicine, National Yang-Ming University, Taiwan

P-45  ESTABLISHMENT OF THE ORTHOTOPIC PRIMARY HUMAN HEPATOCELLULAR CARCINOMA MODEL FOR ONCOLOGY DRUG DISCOVERY

Gang Gray Li¹, Wenwei Li², Dawei Chen², Yiyou Chen², James Christensen¹, David Pocalyko¹

¹Oncology, Pfizer, USA, ²CrownBio

 YIA  P-46  DECREASED EXPRESSION OF NEURENSIN-2 CORRELATES WITH POOR PROGNOSIS IN HEPATOCELLULAR CARCINOMA

Haiqing Ma¹, Xiaoting Liang¹, Jingjing Zhao¹, Hui Wang¹, Jiancong Sun¹, Yibing Chen¹, Ke Pan¹, Minshan Chen², Jianchuan Xia¹

¹State Key Laboratory of Oncology in Southern China and Department of Experimental Research, Sun Yat-sen University Cancer Center, China, ²Department of Hepatobilary Oncology, Sun Yat-sen University Cancer Center, China

P-47  WITHDRAWN

P-48  EFFECTS OF AGE ON SUSCEPTIBILITY TO DIETHYLNITROSAMINE-INDUCED HEPATOCARCINOGENESIS IN CONNEXIN 32 DYSFUNCTIONAL TRANSGENIC RATS

Aya Naiki-Ito, Makoto Asamoto, Shugo Suzuki, Shinya Sato, Tomoyuki Shirai

Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Japan

P-49  ROLE OF WERNER SYNDROME PROTEIN IN RESPONSE TO CISPLATIN-INDUCED DNA DAMAGE IN HEPATOCELLULAR CARCINOMA CELLS

Sun-Young Lee¹, Eun-Sun Kim², Sojin Park², Jin-A Lee², Byungchan Ahn³

¹Ulsan University Hospital Biomedical Research Center, Ulsan University, Korea, ²Departments of Life Sciences, University of Ulsan, Korea, ³Ulsan University Hospital Biomedical Research Center and Departments of Life Sciences, University of Ulsan, Korea

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