P-62  IDO inhibits T-cell function through suppressing Vav1 expression and activation

Xiubao Ren¹

Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, China

P-63  The Relationship between Immunological Markers, Disease Free Survival and Overall Survival in Acute Myeloid Leukemia in North-West of Iran

Zohreh Sanaat¹, Yashar Amizadeh¹, Ali Akbar Movasagpour Akbari¹, Iraj Asvadi Kermani¹, Jalil Vaez Gharamaleki¹, Jamal Eivazi Ziaei¹, Alireza Nikanfar¹, Ali Esfahani¹, S.Hadi Chavoshi¹, S.Hadi Maljaei², Roya Dolatkhah¹

¹Hematology and Oncology, Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Iran, ²Department of Biochemistry, Tabriz University of Medical Sciences

P-64  Determination of warfarin dose requirement in thrombotic and embolic disorders in Iran

Zohreh Sanaat¹, Hamid Tayyebi Khosroshahi², Mehdi Farhoudi³, Javad Keyani⁴, Farhad Khosbin⁵, Majid Tayyebi Khosroshahi⁶

¹Hematology and Oncology, Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Iran, ²Department of Nehrology, Tabriz University of MedicalSciences, ³Department of Norology, Tabriz University of Medical Sciences, ⁴Medicine Faculty, Tabriz University, ⁵Department of Nehrology, Hamedan University of Medical Sciences, ⁶Labrotorist, Loghman Hospital, Tehran

P-65  HDAC inhibitor SAHA inhibits in vitro hypoxia-induced CXCR4 up-regulation in AML cells

Taichi Matsumoto¹, Shiro Jimi², Shuuji Hara³, Yasushi Takamatsu⁴, Junji Suzumiya⁵, Kazuo Tamura⁴

¹Division of Medical Oncology and Hematology and Infectious Disease, Department of Internal Medicine, Fukuoka University, Japan, ²Central Laboratory of Pathology and Morphology, Fukuoka University, Japan, ³Department of Pharmaceutics, Fukuoka University, Japan, ⁴Department of Medicine, Fukuoka University, Japan, ⁵Department of Medicine, Shimane University, Japan

P-66  ASHWAGANDHA LEAF EXTRACT AND ITS COMPONENTS INDUCE DIFFERENTIATION IN HUMAN GLIOBLASTOMAS

Navjot Shah¹, Tetsuro Ishii², Sunil Kaul³, Renu Wadhwa³

¹Graduate School of Life and Environmental Sciences, Tsukuba University, Japan, ²Graduate School of Life & Environmental Sciences, University of Tsukuba, Japan, ³National Institute of Advanced Industrial Science & Technology (AIST), Central 4, Tsukuba, Japan

P-67  ANTI PROLIFERATIVE ACTIVITY OF NEXRUTINE, A HERBAL EXTRACT OF PHELLODENDRON AMURENSE CAUSES CHEMOPREVENTION OF CHEMICALLY INDUCED SKIN TUMORIGENESIS

Kausar Mahmood Ansari, Rahul Kumar, Mukul Das

Food Toxicology Division, Indian Institute of Toxicology Research, India

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