YIA  P-50  MPT0B098, A NOVEL MICROTUBULE-DESTABILIZING AGENT, DISPLAYS ANTI-ANGIOGENIC POTENTIAL VIA AKT/p70S6K/HIF-1α/VEGF SIGNALING IN LUNG CANCERS

Yun-Ching Cheng¹, Wen-Yang Lai², Chi-Yen Chang², Wen-Yu Pan², Jing-Ping Liou³, Ching-Chuan Kuo², Jang-Yang Chang²

¹National Institute of Cancer Research, Nation Health Research Institutes, Taiwan, ²Division of cancer research, Nation Health Research Institutes, Taiwan, ³College of Pharmacy, Taipei Medical University

P-51  INVESTIGATION OF THE DNA-DAMAGING EFFECTS OF BLACK TONER POWDERS IN CULTURED HUMAN EPITHELIAL A549 LUNG CELLS

Volker Mersch-Sundermann¹, Katharina Decker¹, Christina Heinz¹, Albrecht Seidel², Mathias Konzol¹, Ella Goldenberg³, Bernard Grobety⁴, Reto Giere⁵, Richard Gminski¹

¹Institute of Environmental Health Sciences, University Medical Center Freiburg, Germany, ²Biochemisches Institut fuer Umweltcarcinogene, Germany, ³Gernot Grimmer Foundation, Germany, ⁴Department of Geosciences, University of Fribourg, Swiss, ⁵Department of Geosciences, University of Freiburg, Germany

P-52  CIGARETTE SMOKE INDUCED TRANSFORMATION OF NORMAL BREAST EPITHELIAL CELL: ROLE OF ADENOMATOUS POLYPOSIS COLI IN LONG PATCH BASE EXCISION REPAIR

Chanakya Nath Kundu

¹School of Biotechnology, KIIT University, Republic of India

P-53  Expression of HAb18G is Associated with Tumor Progression and Prognosis of Breast Carcinoma

Li Fu¹, Fangfang Liu¹, Yang Zhang², Ling Chen¹, Yu Fan¹, Feng Gu¹, Ronggang Lang¹, Gordon A Pringle³, Xinmin Zhang³, Zhinan Chen⁴, Lifang Cui¹

¹Department of Breast Cancer Pathology and Research Laboratory, Cancer Hospital of Tianjin Medical University, China, ²Cell Engineering Research Centre & Department of Cell Biology, State Key Laboratory of Cancer Biology, Fourth Military Medical University, China, ³Department of Pathology and Laboratory Medicine, Temple University Hospital, USA, ⁴State Key Laboratory of Cancer Biology, Fourth Military Medical University, China

P-54  EVALUATION OF BRUCINE, A PLANT ALKALOID FOR IN VITRO ANGIOGENESIS, APOPTOSIS AND ANTIOXIDANT POTENTIAL IN MCF 7 CANCER CELLS

Sarita Saraswati, Rajani Mathur, S S Agrawal

Genome Research Laboratory, Delhi institute of Pharmaceutical Sciences and Research, India

P-55  Expressions of p16INK4a, p27kip1 and p21WAF1 in differentiating primary adenocarcinoma of endometrium from adenocarcinoma of endocervix

Nor Hayati Othman¹, Farveen Merican Abu Backer¹, Nik Raihan Nik Mustafa²

¹Pathology, Universiti Sains Malaysia, Malaysia, ²Pathology Department, Hospital Alor Star Kedah

P-56  Serological identification of a novel tumor-associated antigen involved in tumorigenesis of ovarian cancer

Suparat Charoenfuprasert¹, Neng-Yao Shih¹, Sy-Jye Leu², Yi-Yuan Yang²

¹National Institute of Cancer Research, National Health Research Institutes, Taiwan, ²Graduate Institute of Medical Sciences, Taipei Medical University, Taiwan

P-57  Testosterone induces DNA damage signaling in response to oxidative stress in prostate cancer cells

Hisamitsu Ide, Yu Jingsong, Lu Yan, Yutaka Kamiyama, Satoru Muto, Shigeo Horie

Urology, Teikyo University School of Medicine, Japan

 YIA  P-58  IDENTIFICATION OF POTENTIAL BIOMARKERS FOR PROSTATE CANCER IN TEARS AND SERUM USING PROTEOMIC APPROACHES

Jing Jing You¹, Anna Fitzgerald², Paul J Cozzi³, Zhenjun Zhao⁴, Peter Graham⁵, Pamela J Russell⁶, Bradley J Walsh⁷, Mark Willcox⁴, Yong Li⁵

¹University of New South Wales; Minomic Pty Ltd., Australia, ²Minomic Pty Ltd. Australia, ³Department of Surgery, St George Hospital, Australia; University of New South Wales, Australia, ⁴Institute for Eye Research, Australia; University of New South Wales, Australia, ⁵Cancer Care Centre, St George Hospital, Australia; University of New South Wales, Australia, ⁶Oncology Research Centre, Prince of Wales Clinical School, Australia; University of New South Wales, Australia, ⁷Minomic Pty Ltd.

P-59  Testosterone and dihydrotestosterone synthesized from DHEA in stromal cells of prostate cancer affect androgen receptor activity

Atsushi Mizokami, Eitetsu Koh, Kouji Izumi, Kazutaka Narimoto, Mikio Namiki

Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Sciences, Japan

P-60  ANTI-IVASION EFFECT OF BITTER MELON LEAF EXTRACT ON RAT PROSTATE CANCER CELL LINE

Pornsiri Pitchakarn¹, Kumiko Ogawa², Shugo Suzuki¹, Satoru Takahashi¹, Makoto Asamoto¹, Pornngarm Limtrakul³, Tomoyuki Shirai¹

¹Department of Experimental Pathology and Tumor Biology, Nagoya City University Graduate School of Medical Sciences, Japan, ²Division of Pathology, National Institute of Health Sciences (NIHS), Japan, ³Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Thailand

P-61  WITHDRAWN

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